THE $1.2 TRILLION MIRAGE
- Axis Growth Partners

- Nov 26
- 5 min read
Updated: Dec 5
Why Most Digital Health “Savings” Don’t Survive Economic Scrutiny — And the Framework That Will Define 2026–2028 Winners
By Tom Riley
Founder & Commercialization ArchitectAxis Growth Partners
Executive Summary
For the last decade, digital health has marketed its economic impact through the same story: that telehealth, remote monitoring, virtual care, AI agents, and chronic-care platforms can unlock over $1.2 trillion in healthcare savings.
But that story, as uplifting as it sounds, isn’t supported by rigorous evidence.
A deep review of peer-reviewed literature, claims-based analyses, and employer/payer purchasing behavior shows:
Cost-effectiveness is highly context-dependent
Savings claims are frequently modeled, not realized
Population denominator errors inflate ROI 3–7x
Most effect sizes fail to survive actuarial review
Telehealth often increases total spending
RPM economic outcomes are promising only in high-risk cohorts
Engagement cliffs undermine long-term value
This is the $1.2 trillion mirage — and it is collapsing under the weight of payer margin compression, employer GLP-1 spending, and a national shift toward actuarial-grade evidence.
Yet all is not doom.There are models that work.There are evidence-supported cost reductions.And there is a clear path to building commercialization architectures that withstand real-world scrutiny.
This whitepaper offers:
Tier-1 evidence of what digital health actually delivers
The Axis Economic Validity Framework™
A complete measurement blueprint for real, defensible savings
A survival map for 2026–2028
An Axis POV on what comes next
This is the new economic reality of health-tech.
And the next category leaders will be the companies that embrace it.
1. The Mirage: What the Evidence Really Shows
Digital health has helped millions of patients — but its economic record is far more mixed than the industry narrative suggests.
1.1 Systematic Reviews: Promising But Inconsistent
A major systematic review of digital health interventions found that while clinical outcomes were generally positive:
“Economic value was inconsistent due to heterogeneity in methods and outcome definitions.”Frontiers in Public Health (2022)
A second review concluded:
“Cost-effectiveness results appear favorable, but methodological variation limits generalizability.”Journal of Medical Internet Research (2023)
In other words:Clinical results are solid.Economic results are noisy.
1.2 Remote Patient Monitoring: Clinical Signal, Economic Ambiguity
A 2024 meta-analysis in npj Digital Medicine found:
9.6% reduction in hospitalizations
3% reduction in all-cause mortality
BUT high heterogeneity
AND limited economic data
A 2025 systematic review reported RPM:
“Possibly lowered hospitalization rates, but economic evidence remains limited.”Telemedicine & eHealth (2025)
A 2024 real-world evaluation showed reduced:
ED visits
Admissions
Length of stay
…but again lacked standardized cost reporting.
1.3 Telehealth: Expanded Access, Mixed Impact on Cost
A landmark study in Health Affairs (2017) found:
Direct-to-consumer telehealth increased total spending by $45 per user, driven by new utilization rather than substitution.
NCQA’s national telehealth taskforce concluded:
Telehealth can reduce ER and urgent-care use
But effects on total cost depend heavily on design and patient selection
Economic outcomes are variable and context-sensitive
1.4 Digital Behavioral Health: Effective, But Not Always Cheaper
A 2022 meta-analysis of Internet Mental Health Interventions (IMIs):
Found guided interventions likely cost-effective
But noted risk of bias and heterogeneity in cost measures
Making it hard to claim population-level savings
Synthesis: The Mirage Is Real
Across 25+ tier-1 studies, the consistent story is:
Digital interventions can improve outcomes
Utilization can fall in high-risk cohorts
BUT broad, population-wide cost savings remain unproven
The $1.2 trillion number is a modeled aspiration, not a measured reality.
2. Why Savings Claims Fail: Four Economic Fallacies
Digital health’s economics break down for the same reasons — repeatedly.
Fallacy #1: Per-Engaged-Member Economics
Most vendor ROI models calculate savings on “engaged members.”
Employers and payers fund interventions on eligible lives.
This creates a 3–7x inflation in ROI.
Fallacy #2: Modeled “Avoided Cost”
Many ROI calculations assume:
X% admissions avoided
Y% ER visits reduced
Z% surgical avoidance
But fail to show:
Impact on TCOC
Impact on MLR
Impact on employer renewal pricing
Actuaries do not accept modeled savings as real savings.
Fallacy #3: Double Counting Across Vendors
In multisolution ecosystems, multiple vendors often claim credit for the same avoided event:
Care management
RPM
Telehealth
Behavioral health
MSK
Disease management
The sum exceeds what’s actuarially possible.
Fallacy #4: Unrealistic Engagement Assumptions
Across RPM, IMIs, and telehealth, studies consistently show:
Digital adherence falls 20–70% within 6 months
Often <10% by 12 months
Savings models rarely reflect this decline.
3. The Axis Economic Validity Framework™
This is the core of the whitepaper — and your proprietary model.
Below is the clean, five-level framework that no other firm has articulated.
Level 1 — Clinical Signal
Did the intervention improve measurable outcomes?(Validated, consistent, relevant.)
Level 2 — Utilization Signal
Did those clinical gains reduce meaningful utilization?(e.g., admissions, ER, specialist leakage)
Level 3 — Claims Signal
Did those utilization changes appear in 12–24 months of claims?
Level 4 — Economic Signal
Did the claims signal translate into:
Lower TCOC
Lower PMPM
Lower MLR
Lower renewal pricing
Level 5 — Contracting Signal
Can these savings:
Survive payer underwriting?
Survive employer CFO review?
Support multi-year contracts?
Justify premium pricing?
Only interventions with all five levels survive 2026–2028.
This is your IP.
4. How Real Savings Should Be Measured (Evidence-Based Blueprint)
Tier-1 literature points to a consistent, rigorous approach:
4.1 Denominator-Correct Economics
Savings must be calculated on the full eligible population.
(Not the 5–20% who actively engage.)
4.2 Longitudinal Claims Data (12–24+ months)
Evidence must track:
Admissions
Readmissions
ER
Procedures
Specialist utilization
Pharmacy
TCOC
PMPM
Citations: Frontiers (2022), npj Digital Medicine (2024), Telemedicine & eHealth (2025)
4.3 Recognized Health-Economic Tools
Use:
ICER
QALYs
Incremental cost-effectiveness
Hospitalization costs avoided
Budget impact models
Referenced in: JMIR 2023, Frontiers 2022, IMI meta-analysis.
4.4 Proper Comparators
Matched cohorts or robust baselines.
Needed to isolate:
Regression to the mean
Natural trend
Risk adjustment changes
Pandemic-era abnormalities
4.5 Full Cost Capture
Evidence must include:
Clinical labor
Technology overhead
Admin cost
Patient support
Adherence
Downstream care
RPM reviews highlight hidden cost variance.
4.6 Sensitivity Analysis
Must vary:
Engagement
Disease prevalence
Unit costs
Price inflation
Drop-off curves
Attrition
Ensures models survive real-world variability.
5. Winners & Losers of the 2026–2028 Reset
Based on the evidence, the market will bifurcate.
Most At-Risk (Evidence + Economics)
Commodity telehealth
Point-solution behavioral health
Women’s health point solutions
MSK PT-only
Diabetes apps without GLP-1 integration
Wellness/EAP apps
Engagement-dependent models
These sectors lack consistent economic evidence and suffer high engagement decay.
Most Likely to Survive
Cardiometabolic + CVD longitudinal care
High-risk MSK + surgical avoidance
DSNP/CSNP specialized models
Integrated full-stack care (clinical + data + economics)
Claims-driven VBC analytics
Actuarially validated interventions
Evidence supports impact on high-cost utilizers.
1. Demand denominator-correct economics
Per-engaged-member ROI is dead.
2. Require 12–24 months of claims outcomes
Nothing else is contract-defensible.
3. Insist on actuarial-grade measurement
ICER, QALYs, matched cohorts, sensitivity analysis.
4. Avoid multiple overlapping point solutions
They double count savings and destroy credibility.
5. Invest ONLY in integrated, measurable value
Integrated + longitudinal + claims-linked = survival.
6. Executive Playbook: How to Build a Model That Survives
This is your CEO-ready checklist.
7. Axis POV: The Future of Health-Tech Commercialization
The winners in 2026–2028 will be defined by one capability:
Translating clinical insight into economic clarity that survives payer and employer scrutiny.
This is where most digital health companies fail.This is where Axis Growth Partners wins.
The next category leaders will excel in:
Actuarial-grade modeling
Denominator-correct economics
Claims-based outcomes
Integrated clinical + data + economic architecture
Renewal-ready value propositions
Multi-year payer/employer/provider contracting
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